Stability, toxicity and differential cellular uptake of protein passivated-Fe3O4 nanoparticles
نویسندگان
چکیده
منابع مشابه
Supporting Information Protein-passivated Fe3O4 Nanoparticles: Low Toxicity and Rapid Heating for Thermal Therapy
Supporting Information Protein-passivated Fe3O4 Nanoparticles: Low Toxicity and Rapid Heating for Thermal Therapy Bappaditya Samanta, Haoheng Yan, Nicholas O. Fischer, Jing Shi, D. Joseph Jerry, Vincent M. Rotello* Department of Chemistry, Molecular and Cellular Biology Program Department of Veterinary and Animal Science, University of Massachusetts, Amherst, Massachusetts 01003 E-mail: rotello...
متن کاملBlock copolymer conjugated Au-coated Fe3O4 nanoparticles as vectors for enhancing colloidal stability and cellular uptake
BACKGROUND Polymer surface-modified inorganic nanoparticles (NPs) provide a multifunctional platform for assisting gene delivery. Rational structure design for enhancing colloidal stability and cellular uptake is an important strategy in the development of safe and highly efficient gene vectors. RESULTS Heterogeneous Au-coated Fe3O4 (Fe3O4@Au) NPs capped by polyethylene glycol-b-poly1-(3-amin...
متن کاملSlight temperature changes affect protein affinity and cellular uptake/toxicity of nanoparticles.
It is known that what the cell actually "sees" at the nanoscale is an outer shell formed of 'protein corona' on the surface of nanoparticles (NPs). The amount and composition of various proteins on the corona are strongly dependent on the biophysicochemical properties of NPs, which have been extensively studied. However, the effect of a small variation in temperature, due to the human circadian...
متن کاملThe Assessment of Toxicity Characteristics of Cellular Uptake of Paramagnetic Nanoparticles as a New Magnetic Resonance Imaging Contrast Agent
Nanoparticles are unique that enable many promising medical and technological applications intheir physical, and chemical properties. It is widely accepted that nanoparticles should bethoroughly tested for health nanotoxicity, but a moderate risk analysis is currently prevented by arevealing absence of mechanistic knowledge of nanoparticle toxicity. The purpose of this study<b...
متن کاملThe Assessment of Toxicity Characteristics of Cellular Uptake of Paramagnetic Nanoparticles as a New Magnetic Resonance Imaging Contrast Agent
Nanoparticles are unique that enable many promising medical and technological applications intheir physical, and chemical properties. It is widely accepted that nanoparticles should bethoroughly tested for health nanotoxicity, but a moderate risk analysis is currently prevented by arevealing absence of mechanistic knowledge of nanoparticle toxicity. The purpose of this study<b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Materials Chemistry
سال: 2009
ISSN: 0959-9428,1364-5501
DOI: 10.1039/b901616c